Sapphire Regenerating Gel Serum

This lightweight gel serum is formulated with advanced cellular bioactives, including Biomimetic Exosomes, Copper Tripeptides, and NAD+, to support visible skin renewal, firmness, and radiance. Its hydrating gel base delivers humectants that leave skin feeling smooth and refreshed while supporting the skin barrier.

Suitable for sensitive, normal, combination and oily skin.

• Improves the appearance of fine lines, wrinkles, and creases
• Helps improve skin radiance and overall complexion
• Optimizes visible improvement after in-office procedures, including microneedling, peels and fillers
• Helps improve the appearance of facial redness

• Biomimetic Exosomes: Vegan, microalgae-derived exosomes that support visible skin renewal and repair by activating cellular communication pathways. Clinically shown to help reduce the appearance of wrinkle depth, improve firmness and elasticity, and enhance radiance and tone over time.
• Copper Tripeptides: Stimulate fibroblast activity to promote collagen, elastin, and glycosaminoglycan (including Hyaluronic) production. Support visible firmness, elasticity, and skin repair, backed by decades of published peptide research. Responsible for the serum’s signature blue color.
• NAD+: key cellular energy cofactor that naturally declines with age, fueling the mitochondrial activity skin needs to power renewal. Supports skin vitality, radiance, and resilience against everyday environmental stress.

Retail Size: 1 FL OZ / 30 ML
Sample Packette: 0.05 FL OZ / 1.5 ML
Back Bar Size: 2 FL / 60 ML

After cleansing, apply to face and neck twice daily. Always apply SPF in the morning. Do not combine in the same routine with retinoids or L-ascorbic acid, as Copper Tripeptides can conflict; use Sapphire AM and those products PM (or vice versa). Sapphire is compatible with 420 C-Stem® due to the tetradecylhexyl ascorbate.

• After 2 weeks, 92% of participants showed a statistically significant improvement in wrinkle fractional area compared to baseline
• After 2 weeks, 92% of participants showed a statistically significant improvement in wrinkle score compared to baseline

• 83% of participants agreed overall skin appearance and quality improved by Week 2
• 92% of participants agreed the serum absorbs quickly and feels lightweight
• 92% of participants agreed their skin felt more hydrated by Week 4
• 92% of participants agreed their skin felt smoother by Week 4†

*VISIA and PRIMOS imaging. †Self-Perception Questionnaire. 4-week pilot clinical study of 12 women ages 35–61, applied AM & PM; no adverse events. ‡Independent finished-product Human Repeat Insult Patch Test (HRIPT). Individual results may vary.